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Instructional
Objectives:
- Define confusion.
- Summarize assessment of confusion.
- State the risk factors for confusion.
- Identify the common causes of confusion.
- List nursing interventions for confusion.
- Name ways to communicate with the confused patient.
Introduction
As
nurses, we are taught to make sure we know the meaning of the terms we
use. When the term "confusion" is used, do we really know the meaning?
According to many authors, the answer to that question is "no". In this
course, we will examine the causes of confusion, especially confusion
in the elderly, how to accurately assess confusion and what to document,
and interventions to be included in the nursing care plan, including how
to communicate with the confused patient. These principles will be illustrated
and reinforced through presentation of a case study. We will also examine
what we, as health care professionals, can learn from our confused patients.
By the end of this course, you will have a clearer understanding of the
term "confusion" as well as how to intervene with elderly patients who
exhibit confusion.
What
is Confusion?
What
do you do to "prove" your assessment of confusion to family members and
friends? How do you feel when your confused patients have periods of lucidity?
Can you accurately assess confusion in your patients? As with many medical
conditions, confusion is not a diagnosis in itself, but frequently the
reason for the presentation of older persons to the emergency room, for
admission to a nursing home, and for transferring from independent living
to an assisted living environment. The prevalence of acute confusion among
elders in long term care has been estimated to be as high as 40%; only
a quarter of these residents were recognized as being confused by staff
nurses. Acute confusion has been said to occur in 10 to 60% of the older
hospital population, and is unrecognized in 33 to 66% of cases. Recent
research on confusion reveals that elderly hospitalized persons who experience
acute confusion are three to five times more likely to die than those
who are not confused. Confusion can mask significant medical diagnoses,
and almost always complicates the patient's course of treatment and recovery.
What
is confusion? How does it manifest in elderly patients? Most authors agree
that confusion can be divided into two categories: acute confusion (also
called delirium) and chronic confusion (also called dementia.) There is
general agreement that acute confusion, or delirium, is temporary, has
an abrupt onset, and may be recognizable by a myriad of inappropriate
behaviors. The behaviors associated with delirium may include inattentiveness,
sleep disturbances, disjointed speech, hallucinations, and other apparent
changes in central nervous system functioning.
Chronic
confusion, or dementia, is a long-term, progressive, and possibly degenerative
process. Early stages of dementia may resemble delirium, and any confusional
state should be considered to be acute and temporary until shown to be
otherwise.
Medical
dictionaries define confusion as a state of disturbed consciousness, with
disruption of thought and decision making capacity. The terminology often
is vague, and accurate diagnosis and consistent treatment may be difficult
as a result. Studies from Japan have also found inconsistent and contradictory
data in the literature, as well as cultural differences in the confusion-related
behaviors that caregivers regard as significant. In any setting, it is
important for the nurse to perform a careful and thorough assessment before
deciding that a patient is indeed confused.
Assessment
Our
assessment of a patient begins either the first time we see that patient
or when we get the information that the patient is to be admitted to our
unit. Some of the time we are so busy that the patient appears before
we have had time to prepare for the admission. In any event, the assessment
of the confused elderly patient encompasses many elements.
Assessment
of the confused patient begins, as does all assessment, with the establishment
of a baseline. With a confused patient, it is imperative to talk to the
family or other caregiver to determine when the confused behavior began.
Some research asserts that the onset of the confusion is more valid than
the assessment of orientation when trying to determine whether the condition
is acute or chronic. Therefore, if a reliable historian is not available,
the nurse may not be able to correctly differentiate between acute and
chronic confusion during the first assessment session, and must rely on
comparison of the present assessment with future assessments to determine
if the confusion is acute or chronic. Medication histories, laboratory
tests, and the results of the physical assessment should be combined to
make a final determination of the confused state. Even with the additional
information, however, accurate assessment may be difficult due to the
many combinations of factors that may cause delirium, especially in interaction
with normal age-related changes in cognition.
Another
problem in accurately assessing the confused patient has to do with our
ever-changing health care system. It is becoming increasingly difficult
to provide compassionate, consistent care for the patients with whom we
come into contact. This is especially true with surgical patients. Many
times the surgical patient is received into the hospital the morning of
surgery, perhaps into an outpatient or outpatient/inpatient area. The
patient is then taken to the surgical suite, then to the recovery room,
and is seen by those on the unit where he will continue his recovery only
after the surgery has been performed. Since just about everyone awaking
from anesthesia is somewhat confused, assessment of the elderly patient
who has had surgery becomes more demanding.
Postoperative
confusion can have many causes, but in the elderly there are several things
to consider when doing an assessment. Mental status at time of admission,
gender, age, amount of postoperative mobility, urinary system health,
and access to a clock or television are some factors to consider when
assessing an elderly postoperative patient. Repeated, accurate assessments
can assist the nurse in determining if, and what type of, confusion is
present. The presence of risk factors in the patient's history should
also be investigated.
Risk
Factors
Risk
factors associated with confusion in the elderly include normal, age-related
changes as well as physical conditions and emotional and social disruptions
in lifestyle. Age-related changes include the diminished ability of the
brain to adapt to both internal and external changes. For instance, as
aging occurs, recent memory may become less reliable than long-term memory.
Think of the difficulty all of us can encounter in remembering to take
medication four times a day. Have you ever been given a prescription for
an antibiotic, for example, ordered to take it four times a day for ten
days, and had to make a checklist after the third or fourth day so that
you would remember to take it?
Physical
conditions that are risk factors for the development of acute confusion,
or delirium, include:
- nutrition, including fluid and electrolyte imbalances
- medication reactions or interactions o altered metabolic function,
including diabetes mellitus, hypoglycemia or hyperglycemia, and thyroid,
parathyroid and pituitary disturbances
- cardiovascular alterations such as decreased cardiac output, cardiac
disorders, and vascular disorders
- infections
- urinary alterations
- abnormalities in temperature regulation such as hypothermia, hyperthermia.
Increased
interest is being paid to nutritional factors in the development of both
acute and chronic confusion. Vitamin B 12 deficiency has long been suspected
as a cause for confusion in the elderly, and has been studied for its
relationship to the development of Alzheimer's disease. B 12 supplementation
may improve aspects of cognitive function, but rarely has been noted to
reverse dementia. Thiamine deficiency has been noted in significant numbers
of Alzheimer's patients and may affect their cognitive function. Screening
for thiamine levels should probably be considered in more cases of confusion,
given the propensity for thiamine to be depleted by use of diuretics.
Research has also been conducted on the use of plasma chain-breaking anti-oxidants
(which include alpha- and beta-carotene as well as Vitamins A, C and E)
to improve cognitive function in Alzheimer's disease. Use of Vitamin C
and E supplements has been suggested to protect against vascular dementia
and to improve cognitive function in general in later life. The beneficial
effects may indicate that increased free-radical activity has a common
role in the cognitive impairment seen in various dementing conditions,
and may suggest an avenue for more aggressive treatment. Unfortunately,
rigorous research in this area is lacking.
The
elderly are more likely than younger patients to exhibit cognitive impairment
from taking medications; these result from age- and disease-associated
changes in brain neurochemistry, as well as changes in the body's overall
ability to handle various drugs. Delirium is the most commonly seen cognitive
disturbance related to drug toxicity, but dementia has also been reported.
Drugs have been implicated as the cause of acute confusion in 11 to 30
% of cases among elderly hospitalized patients, and medication toxicity
occurs in up to 12% of patients presenting with possible dementia. Central
nervous system toxicity may be dose dependent, resulting from interference
with neurotransmitter function.
Almost
any drug can cause delirium, especially in a vulnerable patient. Anticholinergic
medications are important causes of both acute and chronic confusional
states, but multiple anticholinergic drugs are still commonly prescribed,
especially to nursing home residents. Recent studies have indicated that
the total anticholinergic burden may determine the development of confusion
rather than any single medication. In evaluating a patient's medication
history, the nurse should keep in mind that anticholinergic effects have
been identified in many drugs other than those classically thought of
as having significant anticholinergic effects.
Psychoactive
drugs are important causes of delirium. Acute confusion was a major complication
of treatment with the tricyclic antidepressants, but is less often seen
with the newer selective serotonin reuptake inhibitors (SSRIs) and atypical
agents. Narcotic agents can cause delirium in postoperative patients;
and the neuroleptics and long-acting benzodiazepines are known to cause
or increase delirium and dementia.
Drug
induced confusion with non-psychoactive drugs is most often idiosyncratic
in nature, and as a result the diagnosis is easy to miss. Cardiac medications
such as digoxin and beta blockers, corticosteroids, histamine H2 receptor
antagonists, nonsteroidal anti-inflammatory drugs (NSAIDS), and antibiotics
can all cause or exacerbate confusion.
Among
other specific causes of confusion that are often seen in the nursing
home are dehydration and urinary tract infection, and should be suspected
in any resident showing an abrupt change in mental status. In the hospital
setting, thyroid dysfunction, vitamin B-12 and other vitamin deficiency,
and normal pressure hydrocephalus are among the differential diagnoses
to be considered.
Emotional
and social disruptions in lifestyle include confinement to a restricted,
unfamiliar area; absence of needed prosthetics (hearing aid, glasses,
dentures) or items that complete body image (purse, cane, makeup); loss
of stable environment and contact with family; enforced bed rest; disrupted
patterns of daily living, especially sleep; loss of control over body
processes; relocation; and recent loss of significant person or possessions.
Causes
What
causes confusion, especially confusion in the elderly? Many authors agree
that confusion is the most common complication of hospitalization of the
elderly. There is also evidence that elderly patients are sometimes confused
following surgical procedures, with anesthesia thought to be a primary
causative factor.
The
risk factors that can predispose the elderly to confusion can also be
considered causes. Age-related changes, physical conditions, and emotional
and social disruptions in lifestyle may be implicated. Many of the changes
in mental status may be related to the side effects and interactions of
the numerous drugs usually prescribed for people in this age group. When
hospitalized, the elderly are confronted with the additional stressors
of changes in health status as well as separation from family, familiar
environment, and familiar routines.
Causes
of confusion may be organized into three categories: systemic, mechanical,
and psycho-social/environmental. The first category, systemic, includes
factors that interrupt normal brain functioning through the alteration
of metabolic processes in the brain. As noted above, this category would
include blood sugar abnormalities as well as hormone changes. The second
category, mechanical, refers to a blockage or other physical restriction
of normal brain functioning, such as those associated with stroke or traumatic
injury. Finally, psychosocial/environmental factors are non-biological
in origin and tend to diminish personal meaning. Loss of loved ones and
changes in residential setting and circumstances fall into this third
category.
Symptoms
It
is difficult to list symptoms for confusion, either acute or chronic,
since that list becomes a "laundry" list containing just about every vague
symptom known to the medical profession. However, consideration of the
most common and well-known symptoms gives a convenient starting point
from which to perform the assessment.
Sometimes
the confused person can't function intellectually or deal with the environment
in the usual way. They may be disoriented to time, place, and/or person,
or develop inaccurate perceptions, such as thinking a television image
is a person. They may have delusions, use poor judgment, or forget, especially
if they are hospitalized. Social interactions may become a problem; when
they can't communicate meaningfully and have difficulty maintaining their
attention, they may become angry, belligerent, withdrawn, uncooperative,
or restless. Health care professionals as well as family may find it impossible
to reason with the confused patient. Behavioral changes, which may be
out of character, may occur. The patient may become hyperactive and display
agitation, excitability, and/or irritability. Conversely, they may become
hypoactive and display lethargy, somnolence, apathy, and/or reduced activity.
Additionally, a confused patient may periodically exhibit both hyper-
and hypoactive behaviors.
Some
differentiations may be made between the clinical features of acute and
chronic confusion with regard to onset, course, progression, duration,
awareness, and alertness. Acute confusion often has an abrupt onset associated
with an identifiable risk factor or cause. The course is short with diurnal,
or daily, fluctuations in the symptoms; confusion may appear worse at
night, in the dark, and on awakening. The associated cognitive and behavioral
deficits show no clear pattern of progression, despite their variability
throughout the day. Duration may range from hours to less than one month.
Awareness of the environment may be reduced, and level of alertness may
fluctuate from lethargic to hypervigilant.
Chronic
confusion associated with dementia, in contrast, has a slower, more generally
insidious onset, again depending on the cause. The course is long with
no marked diurnal effects, and symptoms are progressive but relatively
stable over time. The progression is slow but fairly even, and the duration
is months to years, with no expectation of recovery of function. With
chronic confusion, the patient is likely to exhibit adequate awareness
of surroundings and a generally normal level of alertness.
To
complicate matters even further, an acute confusional state may develop
in a patient already suffering from chronic dementia, as a result of factors
such as hospitalization, development of an acute illness, or a medication
change. Detection of delirium superimposed upon dementia can be particularly
challenging for both nurses and physicians. Delirium with dementia can
be associated with new onset incontinence, depression, and weight loss;
patients with both diagnoses are much more likely to be re-admitted to
the hospital within thirty days than patients with delirium alone are.
The causes of the "new" delirium must be identified and addressed regardless
of the baseline cognitive status of the patient. Even after appropriate
treatment, however, the patient may not return entirely to their baseline
level of function.
A
phenomenon associated with confusion that may be observed in patients
with dementia is "sundowning" or "sundown syndrome," a constellation of
behaviors associated with increased agitation and confusion that occurs
in the late afternoon. Specific etiologic hypotheses that relate to sundowning
behaviors include disruptions in regulation of melatonin, disturbances
in Rapid Eye Movement (REM) sleep, episodes of sleep apnea, and a deterioration
of an area in the hypothalamus. Decreased visual acuity related to waning
natural light may lead to misperceptions of the environment, and reduced
levels of structured activities associated with mealtime and staff shift
changes have also been implicated. Management can include the identification
and treatment of any physiologic factors, low doses of specific psychotropic
medications, and non-pharmacological interventions, such as restriction
of daytime sleep, exposure to bright lights during the day, and moderate
but consistent activity schedules.
Nursing
Interventions:
Communication
As
you remember from nursing school, the way the nurse communicates can set
the tone for the patient's experience with the medical professions in
general, and influence the outcome of medical interventions. When the
elderly person is admitted to the hospital, the nurse must recognize the
changes that this has caused in that person's life. The nurse should also
recognize what the age difference may mean in terms of acceptance of care.
Our parents' and grandparents' generations have seen tremendous advances
in every aspect of life; things that we take for granted. For instance,
the telephone was invented in 1876, 125 years ago. Anyone born before
1960 (just 40 years ago) will probably remember the black desk-type telephone
or even separate hand and mouth sets. The automobile was first mass-produced
in this country less than 100 years ago, and air travel did not become
commonplace until well after World War II. The television did not become
a common household item until the 1950's, and our children are amazed
that television shows were not in color when we were growing up. The advances
in medical technology are too numerous to list; however, before 1950,
most physicians were general practitioners, antibiotics were just being
utilized routinely, and CT scans and MRIs had not even been dreamed of.
Should we then be surprised at the fear and helplessness an elderly person
may feel when admitted to the hospital? In today's world of medicine,
even the hospital room can be scary to the uninformed.
Let's
look at a hospital room through the eyes of a patient, starting with the
call system. These will vary among hospitals and areas of the country,
but most are all inclusive with the call button, the television control,
and the bed control all on the same panel. Perhaps the call system is
on a hand-held control or on the bed rail. Next time you are in a patient
room, try to look at that control as if you'd never seen one and think
about what you see. Of all the additional equipment that may be used,
the most frightening for the elderly patient may be the intravenous set-up,
especially if a pump of some kind is used. Most of the pumps have blinking
lights as well as warning "beeps". With the constant changes and upgrading
of systems, they have been hard enough for nursing professionals to learn.
How intimidating they must be to the uninitiated!
Of
course, there are always those elderly patients that break all the rules
when it comes to knowledge of medical facts and facilities. In fact, there
are many elderly adults (in their 80s and 90s) that can run circles around
the most energetic nurses! The point is to assess the patient's level
of knowledge and then communicate on their level. This can alleviate much
of the confusion they feel in relation to their surroundings. Confusion
can also cause some bizarre behaviors on the part of the elderly patient.
Crying out, banging on the side rail, and trying to get out of bed are
some of the behaviors that assist us in making the diagnosis of confusion.
However, contact with another human being may be all that is needed to
bring them back to the present.
Confusion
is increased if the nurse communicates alarm by tone of voice and actions.
The patient may become agitated and unmanageable and may agitate the nurse.
A
relaxed approach to this kind of situation is difficult, yet may be the
only one that is workable. The nurse should speak in a soft, low voice,
telling the patient who is there, and make simple, reassuring statements.
Holding the patient's hand to further the feeling of safety and permit
some organization of thoughts is appropriate if the nurse is comfortable
with this intervention. It is important that the actions of the nurse
reflect true feelings so that the patient is reassured and not even more
confused.
When
the patient does not fully comprehend what is happening, the nurse's facial
expression, touch, and tone of voice can create a more comfortable atmosphere.
Frequently, all that the confused elderly patient needs is extra time
and patience or, truly, some "tender loving care."
Consider
the example of the nursing student. Students, especially during the first
clinical rotation, have more time to spend with the patient. Once personal
hygiene is completed and the patient is comfortable in a chair, the student
can, many times, sit with the patient and talk. Report at the end of the
shift may, then, go something like this, "I don't know why the nurses
think this patient is confused. He didn't seem at all confused to me and
I spent the entire morning with him."
Family
members are often embarrassed and distressed by confusion in their elderly
relative, especially if that person was not previously confused. The family
may need some type of comfort, a touch or word of support, so that they
can interact with their loved one in a satisfactory way. They need to
know their mother or father is experiencing a state that is common and
almost predictable in the elderly hospitalized patient. Methods of communicating
that have worked with the patient, such as touching and reassuring, will
be beneficial to the family.
Since
information is still being gathered during this intervention phase, care
must be exercised. Many patients appear to give accurate data, but they
may confabulate to cover up a loss of memory. In cases of doubt, it is
best if the information can be confirmed by a family member.
An
additional problem that may appear as confusion is that words and actions
have different meanings to people of different ages and cultures. The
nurse must determine what the patient means, and what the patient understands.
A client 40, 50, or 60 years older than the nurse is probably viewing
the world from an entirely different perspective. A 90-year-old man who
remembers when medicine was primitive and a physician was called only
as a last resort when someone was dying, may view the efforts of modern
scientific medicine with suspicion and may not follow the necessary medical
regimen. The patient may appear confused but in actuality is only acting
on his earlier belief that medicine and physicians are really unable to
help. He may not be able to accept the opinions of a young physician who
has long hair or a beard or who is of a different race. Some older patients
react negatively to a nurse who is a man, because they have always perceived
nursing as a profession for women. In all these instances, no matter what
the nurse feels or thinks, professionalism in handing the situation is
necessary.
Specific
Interventions
Nursing
interventions should focus on priority patient care issues. Safety, privacy,
reduction of stimuli, frequent monitoring of confusion status, and reality
orientation are all important areas when planning the nursing care of
the confused elderly patient.
Safety
is one of the most important foundations of good patient care. How to
keep a confused elderly patient safe may be the biggest job the nurse
has, especially if the confusion leads to significant agitation. There
have been three traditional ways to maintain safety: drug therapy, restraints,
and use of a sitter or family member to stay with the patient at all times.
Acute
treatment of agitated patients has traditionally relied on antipsychotic
medication, primarily haloperidol (Haldol), alone or in combination with
benzodiazepines, usually administered IM. The recommended adult dose of
Haldol 2 to 5mg IM is likely to be poorly tolerated in the elderly confused
patient, and a more prudent approach would be 0.5 mg of Haldol combined
with a like amount of benzodiazepine; higher doses only result in increased
adverse extrapyramidal effects.
Benzodiazepines
alone are also effective in controlling acute agitation also, and are
better tolerated than the typical antipsychotics. IM lorazepam (Ativan)
acts as quickly and as effectively as IM haloperidol in most instances,
and oral lorazepam acts much more quickly than oral haloperidol. Recent
studies have shown that lorazepam with risperidone (Risperdal) is generally
equivalent to lorazepam with IM haloperidol in controlling acute agitation;
given the greater tolerability of risperidone, this combination may eventually
become the treatment of choice. Several medications in addition to the
ones listed above have been used for longer-term treatment of agitation
in the chronically confused patient. Propranolol (Inderal) has been used
to control impulsivity and agitation, but use must be monitored carefully
for potentially dangerous effects on cardiovascular function. Both carbamazepine
(Tegretol) and divalproex (Depakote) have been used effectively, with
divalproex often chosen due to its relatively benign side effect profile.
Restraints
have become a controversial intervention with much research devoted to
the topic. According to a recent study on confused elderly patients, restraints
are used about 40% of the time, with the vest (Posey) restraint being
the most commonly used. The probability of being mechanically restrained
increases if the elderly patient is new on the unit, presents a risk for
falls or other injuries, or requires more extensive nursing care.
If
restraints are chosen as a nursing intervention, patients should be observed
for restlessness, since agitation has been noted to increase when the
elderly patient is restrained. Use of restraints requires a physician's
order, and documentation requirements are significant. Careful and frequent
monitoring of the patient is imperative. See Figure 1 for guidelines
on using restraints properly.
FIGURE
1
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