Psychiatric
Emergencies: Conditions that Impair Functioning - Organic Brain Syndromes
The
conditions that make up this group of psychiatric emergencies have mixed
psychological and physical components. They are the result of organic
brain dysfunction which may present as confusion, memory disturbance,
disorientation, altered levels of consciousness, motor difficulties such
as poor balance or incoordination, decreased impulse control, impaired
judgment, and disturbances of physiological functioning which could lead
to death. These states may stem from alcohol or drug overdose, withdrawal,
or toxic or idiosyncratic reactions; or they may be due to brain dysfunction
from trauma, vascular infections, disturbances in metabolic functioning,
or neoplasms of the central nervous system.
These
and a wide variety of other medical conditions may present with similar
symptom profiles. It is essential to have a thorough physical examination
to rule out pneumonia, thyroid imbalance, diabetes and other general medical
conditions that can affect brain function.
Alcohol
Related Problems
Alcohol
is the most abused drug in the United States. Two of the most common medical
problems are found among persons who abuse alcohol - acute intoxication
and withdrawal from continued use. These conditions are considered
both psychiatric and medical emergencies because if left untreated, they
could lead to the death or injury of the person or others due to the impaired
behavior resulting from the alcohol. A high percentage of fatal accidents
occur with a driver of a motor vehicle under the influence of alcohol.
The risk of suicide and homicide increases significantly when alcohol
is used.
Acute
alcohol intoxication: An uncomplicated picture of an acutely intoxicated
person includes alcohol odor, unsteady gait, slurred speech, and sometimes
nausea, dizziness and vomiting. Giddiness and uninhibited speech and behavior
are common. This person usually needs only to be protected, prevented
from drinking more, escorted home or to an overnight facility to "sleep
it off," and observed in case of other complications.
More
serious degrees of alcohol intoxication are suggested by central nervous
system disturbances such as incoordination, dysequilibrium and impaired
level of consciousness. Behavioral warning symptoms include excessive
crying, laughing, hostility, aggressive behavior, depression and seizures.
Medical evaluation and treatment are indicated.
In
addition to the physical examination and monitoring of vital signs, the
following questions help in the evaluation of an acutely intoxicated person.
The individual or other informants may be able to give the answers, which
must always be regarded with some degree of skepticism.
- How long has the person been drinking? What? How much? When was the
last drink?
- What is the drinking history over a period of time? Treatment?
- Previous seizures?
- Delirium tremens? Hallucinations?
- Has the person taken Antabuse within the past five days?
- Any other drugs recently or concomitantly with the alcohol?
- What other physical conditions are known - ulcer, diabetes, heart
condition, etc.?
- Have any other injuries or accidents occurred during the drinking
bout - falling down, struck by another person or object?
- Is there a history suggesting significant psychiatric disorder?
The
very young, the elderly, and people with organic brain damage are unusually
susceptible to alcohol. Alcohol taken with other drugs may produce disorientation
to time, place and person. This may produce panic, which should be treated
by a calm attitude and protection until time helps to wear off the effects.
A person who is combative or assaultive while drunk may be suffering from
other underlying conditions. He/she may have ingested drugs, especially
the hallucinogens or stimulants. Gross disturbance, belligerence and confusion
can result.
Many
people use alcohol as self-medication. If it is being used to ward off
a psychotic state, this becomes more apparent as the acute intoxication
subsides. Alcohol lowers defenses and inhibitions and can result in rage
reactions, suicidal behavior and agitation. Many interpersonal confrontations
take place during drinking with assault and violence the outcome. Spouse
and child abuse are often linked with alcohol intoxication.
Those
who become significantly depressed while drinking need to be evaluated
for the degree of intoxication and for suicide potential. Driving a motor
vehicle while intoxicated may result in planned or unintentional accidents
and death.
A
seizure in an intoxicated person may indicate the beginning of delirium
tremens or an underlying seizure disorder. Some people with temporal lobe
epilepsy are unusually sensitive to alcohol. The seizure often takes the
form of an unprovoked rage reaction that results in fights or assaults
on property.
Emergency
management of the patient with acute alcohol intoxication: The health
team works together to help the patient during the acute medical situation.
His/her situation may be compounded by behavior that is uncooperative,
aggressive, abusive or demanding. It is important during this period not
to take this behavior personally or to react with retaliation. As with
any person with an acute brain syndrome, the person is "not in his
right mind." Action includes:
- Approach with a nonjudgmental attitude of helpfulness, firmness and
consistency
- Don't be intimidated or antagonized by belligerence, hostility or
uncooperativeness
- Speak calmly, firmly with reassurance
- Don't laugh, ridicule or challenge
- Use safety precautions and enough staff with a potentially assaultive
person
- Maintain observation and check vital signs frequently
- Keep a patent airway - remove foreign objects from mouth and throat,
such as mucous, blood, vomit, dentures
- Draw blood for alcohol and drug level determination if indicated
- Examine for injuries and other physical conditions
- Sedate the restless, noisy, belligerent
- Allow the person to "sleep it off" while under observation
- Hospitalize if indicated
- When the patient is conscious, offer fluids by mouth, especially fruit
juices
- After acute treatment, refer to longer-term treatment resources.
Alcohol
withdrawal states: Those who are physically dependent on alcohol develop
characteristic withdrawal symptoms within 12-24 hours after the blood
alcohol begins to drop. The person may have stopped drinking or have lessened
the usual amount of intake. Withdrawal symptoms range from relatively
mild, though miserable, to reactions that are severe and life threatening.
Delirium tremens (D.T.'s) is the most extreme withdrawal reaction, with
a death rate that has been estimated from 5-30%.
Planned
withdrawal from alcohol occurs when individuals gradually or abruptly
decrease alcohol intake. They may or may not seek medical attention with
the subsequent reactions. Planned withdrawal is also called detoxification.
Many communities offer both medical and non-medical options to help with
safe withdrawal.
Unplanned
withdrawal occurs when an addicted person is suddenly cut off from alcohol
through lack of funds, lack of supply or through the decision to quit
abruptly. Patients who are hospitalized for medical conditions or accidents
may develop withdrawal symptoms while being treated. This may drastically
affect their recovery.
Signs
and symptoms of acute withdrawal may include "the shakes:" coarse tremor
of hands, tongue and eyelids that is more apparent with movement; anorexia,
nausea and vomiting; malaise and weakness; anxiety, sense of dread and
shakiness, uneasiness, jumpiness; autonomic hyperactivity - tachycardia,
sweating, increased blood pressure; depressed mood; irritability; insomnia
or disturbed sleep with bad dreams; orthostatic hypotension and dizziness;
and distortions in visual perceptions. These symptoms generally begin
about 24 hours after the onset of abstinence and reach their peak in another
24 hours, although they may occur at any time within the next fifteen
days.
Moderate
to severe withdrawal syndromes in otherwise healthy individuals can be
handled on an outpatient basis through supportive measures that include
bed rest, adequate fluids, adequate vitamins and nutrition, continued
abstinence from alcohol and planned short-term use of minor tranquilizers
(Librium, Valium, Vistaril).
The
medical and psychiatric crisis aspects of withdrawal indicate hospitalization
when:
- The person wants to quit drinking but has a poor social support system.
There is no one to help or there are active drinkers who would discourage
the effort to quit.
- There is a history of previous severe reaction to withdrawal and the
person fears return of the D.T.'s or other frightening symptoms.
- The person has already started to withdraw with symptoms of anxiety,
seizures, extreme agitation, hallucinations or delusions.
- The person is physically debilitated or has an alcohol related condition,
such as cirrhosis, peripheral neuropathy or pneumonia. Wernicke's syndrome
from thiamine deficiency requires immediate treatment to prevent permanent
brain damage. (In many settings, it is routine to administer at least
one dose of thiamine IV or IM to all alcoholic patients admitted to
the hospital with altered mental status.)
Alcohol
withdrawal delirium: This condition is generally known as delirium
tremens or the D.T.'s, an acute brain syndrome that is usually due to
the cessation or reduction of alcohol consumption in an addicted person.
It occurs most often in those with a history of heavy drinking over a
3 to 5 year period or longer. Delirium tremens is a medical emergency.
It is a serious and dangerous reaction characterized by autonomic hyperactivity,
seizures, agitated behavior with restlessness and overtalkativeness, coarse
tremor, confusion and disorientation, delusions, and hallucinations -
most often visual and tactile and often terrifying.
Symptoms
often get worse at night. D.T.'s result from a disturbed metabolic state.
They require adequate medical treatment and skilled nursing care. Successful
recovery occurs within 3 to 10 days. After a period of prolonged sleep,
the patient wakes refreshed, oriented and free of hallucinations. Alcohol-withdrawal
delirium is often precipitated by abrupt alcohol withdrawal due to trauma
or infection. The patient may be in the hospital for these reasons when
the withdrawal syndrome begins. Chronic alcohol abusers are poor surgical
risks because of lowered resistance and organ damage. They have a poor
response to anesthesia. If excessive use of alcohol is known, the metabolic
balance of the patient can be evaluated before surgery. Often, the impending
D.T.'s are not recognized until postoperatively, which gravely affects
recovery.
Nursing action in treatment of delirium tremens: The problem
of this disorder is the acute medical syndrome with subsequent behavioral
manifestations, including agitation, combativeness, terror and disorientation.
The
goals of treatment are to control the delirium, lessen agitation,
restore fluid and electrolyte balance, and control seizures. A combined
medical and nursing approach is necessary to control the terror of the
delirium and to restore health.
Actions:
- Provide a well-lit room with few external stimuli.
- Reassure and reorient repeatedly.
- Limit the number of staff and visitors.
- Protect the patient from self-injury or acting on the delusions or
hallucinations by getting out of bed, running through windows, etc.
- Speak in a calm, soothing voice.
- Use mechanical restraints only when absolutely necessary as the patient
may fight against them.
- Administer prescribed medication to decrease agitation - Vistaril,
Thorazine, Librium, Valium, paraldehyde and chloral hydrate may be prescribed,
depending on the medical regimen. The goal is to provide rest and sleep,
without inducing coma or stupor.
- Administer and record appropriate intravenous fluids with necessary
vitamins and minerals added.
- Prevent or treat seizures by administering appropriate anticonvulsant
medication.
When
the patient has recovered from this acute emergency situation, many treatment
teams make concerted efforts to arrange for longer-term treatment of the
alcoholism and other problems. Some patients are motivated and able to
follow through. Others return to treatment units in desperate condition
again and again. This can lead to discouragement and cynicism among the
staff if their feelings and the dynamics of this difficult condition are
not reviewed and discussed.
Drug
Abuse Related Problems
Drugs,
other than alcohol, are also often the cause of psychiatric and medical
emergencies. The most frequent drugs of abuse include:
- The opiates - opium, morphine, heroin, codeine, Dilaudid, paregoric,
methadone, Demerol and Darvon.
- Central nervous system depressants - the barbiturates and similarly
acting drugs (other than alcohol), bromides, anesthetic gases and vapors,
chloral hydrate, paraldehyde, methaqualone, Placidyl, Miltown, Equanil,
Valium and Librium.
- Central nervous system stimulants - cocaine, amphetamines and
similarly acting substances, dextroamphetamines, methamphetamine (speed),
Ritalin, Adderal, and many combinations of "diet pills."
The
main problems arising from use of these substances are 1) acute intoxication,
which is also referred to as overdosing or poisoning, planned or unintentional;
and 2) withdrawal symptoms on cessation of the drug-taking.
Acute intoxication or overdose: This is the result of sufficient
intake of the drug to produce signs and symptoms of distress. An organic
brain syndrome occurs, which ranges from moderate to severe. The acute
organic brain syndrome may be characterized by disorientation; impairment
of memory, judgment, and intellectual function; emotional lability; decreased
coordination; dysarthria (slurred speech); fine tremor; and unsteadiness
of balance and gait.
The
first step when an overdose is suspected is to assess the seriousness
of the potential emergency. A person may overdose on drugs as a suicide
attempt, through mistakes in self-medication, through confusion because
drug potency is increased or by a combination of drugs and alcohol. The
range of seriousness is:
- Life-threatening - immediate medical care is needed to prevent death
- Serious - requires hospitalization for treatment and further evaluation
- Potentially serious but not requiring hospitalization
- Not immediately dangerous but requiring evaluation and possible referral
The
serious complications of acute drug intoxication are coma, respiratory
failure and circulatory collapse. Every case of drug overdose is regarded
as potentially serious until medical attention is given. The patient's
physical condition can shift rapidly to a more life-threatening level.
People
found unconscious from drug overdose must be taken immediately to an emergency
room. Mouth-to-mouth resuscitation, oxygen and other life support systems
may be necessary en route. Specific treatment for the drug overdose will
vary with the substance and the physiological response. At this point,
the emergency is a medical one.
Part
of the evaluation is a drug history, either from the person, if possible,
or those who know him/her. This includes specific drug taken, how much,
whether and when physician prescribed; use of street drugs; medical history,
especially of diabetes and seizure disorders; concomitant use of alcohol;
known drug use; and previous overdoses and outcomes. During the medical
history and evaluation it is important for the nurse to establish if the
patient has ever used intravenous drugs. In consideration of community
health problems and the rapid spread of disease, many psychiatric emergency
facilities are screening patients for AIDS virus and hepatitis C. It is
important for the patient's safety and proper treatment as well as for
the safety of the health care workers and other patients.
After
the person has been adequately treated medically, he/she should be evaluated
in terms of emotional state. If the overdose was suicidal in intent, the
person should be evaluated further for suicide risk. Referral to special
drug facilities or mental health facilities is indicated but may or may
not be acted upon.
Withdrawal
from drugs: An abstinence or withdrawal syndrome occurs after cessation
of taking a drug to which one has become addicted. The symptoms vary with
the specific drug, as does the treatment. At this point the primary concern
and treatment are medical.
Withdrawal
treatment for barbiturates should take place within a hospital because
of the difficulties in reducing the amount of medication needed, the likelihood
of seizures and the period of transient psychosis which is marked by confusion,
disorientation, agitation and hallucinations. Nurses provide highly skilled
care during this time, using physical skills as well as basic care for
disturbed persons with the above behavior.
The
term "bad trip" was coined several decades ago to describe a negative
outcome of drug intake that still can occur today. Instead of the anticipated
pleasant experience, there is a state of unpleasant-to-horrifying perceptions
and feelings. Panic and confusion predominate. The person may develop
a toxic psychosis with agitation, hallucinations, and delusions. This
may be precipitated by one of the central nervous system stimulants or
by a hallucinogen.
Amphetamines
are in the former category and hallucinogens include mescaline, psilocybin,
D-lysergic acid diethylamide (LSD), STP, phencyclidine (PCP), marijuana
and hashish. PCP is a particularly powerful agent that can produce extreme
agitation or a state resembling a catatonic reaction. Many times treatment
within a hospital will be necessary because of the severity of the symptoms
and the unpredictability of the person's actions. Anticholinergic drugs
include the active agents of atropine and scopolamine. These are easily
obtained as nonprescription drugs, often for sleep problems.
These
drugs are taken for the experiences they produce and are marked by perceptual
changes. Body, time and reality distortions become a problem if the person
loses the perspective that these are drug-induced and develops a panic
reaction. Psychosis may result, and this is when the experience becomes
a psychiatric emergency. Symptoms include increased paranoid ideation
which results in terror and potential aggression; fear of going crazy;
and impaired judgment, resulting in injuries from such behaviors as running
into traffic or believing one can fly out the window.
The
need for treatment of these reactions depends on the severity. Many of
them are time-related. As the drug wears off, so do the disturbing experiences.
If medication is needed, it will probably be Valium by mouth or injection.
Use of barbiturates and phenothiazines (Thorazine) is contraindicated.
This is true also if the drug reaction is from an anticholinergic agent.
Acute reactions may be treated by quiet, supportive talking with the panicked
person. Drug-experienced friends and counselors can be very helpful during
this time to "talk the person down." Helpful steps include the following.
- Find a quiet place where external stimuli are minimal. If in the E.R.
find a place away from the mainstream.
- Do not leave the person in isolation or in a potentially unsafe place.
- Establish eye contact, and use a calm, gentle attitude and voice.
- Remind the patient that the experiences are drug-induced and will
wear off. Repeat and reassure over and over and over.
- Reorient to time, place and person.
- Stay in the immediate "now."
- Instruct the person to keep eyes open and focus on external reality
- an object or candle.
- Keep friends and other drug-experienced people around.
- Gently hold or touch the person if this doesn't seem threatening.
- Encourage the person to talk about the immediate sensations and experiences
to decrease the sense of alienation.
- Explain reasons for medication, if needed, especially by injection.
Problems
and Goals
The
initial and most pressing problems associated with substance abuse are
the physical results of the organic brain syndrome. The physical problems
include intoxication, withdrawal and undesired responses to the drugs,
and the basic cause(s) of the brain pathophysiology whatever that cause
may be. Physical complications may include respiratory depression, cardiovascular
collapse, shock, temperature dyscontrol, renal problems, and seizures.
The
short-term treatment goals are:
- Restore physiological equilibrium by careful detoxification and withdrawal;
prevent further medical complication, treat current conditions
- Restore impulse control
- Prevent suicide or violent behavior
- Establish communication
- Increase reality testing
- Develop plans for long-term treatment
- Establish working relationships with family and significant others
- Dehydration to fluid overload
- Changed electrolyte balances
Emergency
medical treatment can save lives, but does not solve the problem of drug
and alcohol abuse and addiction. To help prevent future emergencies and
possible death by substance abuse, the following long-term goals are
identified:
- Recognition by the person of the significance and dangers of continued
substance abuse
- Improved health - abstinence or decreased use
- Increased social participation and meaningful relations with others
- Discontinuance of criminal behavior
- Improvement of family relationships
- Increased use of job potential and skills
- Alternative ways of coping with stress and needs
Nurses
are active participants in the emergency treatment given in the emergency
room, intensive care unit and medical floor. They are also involved in
special drug-treatment clinics, methadone programs and community mental
health programs that help the person with the very complex problems of
substance abuse.
Cerebral
Dysfunction from Other Causes
As
noted above, the presenting symptoms of brain trauma, bacterial and viral
infections, metabolic problems, brain tumors, epilepsy, and a host of
other medical conditions can be very similar to those resulting from alcohol
and drug use. Consequently, it is imperative that anyone presenting with
cognitive or behavioral disturbances be given a thorough examination as
soon as possible, which includes a detailed history and lab tests. These
patients may exhibit behavior that is disruptive, combative, uncooperative
and disoriented. General nursing actions can be used to handle the immediate
situation and assist in the differential diagnosis.
Often
family members are highly distressed about the changes in their loved
one, and they need support and realistic reassurance. They may also be
helpful in supplying needed information and in staying with and comforting
the patient.
Traumatic
Brain Injury
Traumatic
brain injury is one of the "organic" group of psychiatric disorders, in
that the physiological changes that cause it are clear and relatively
well understood. It is frequently seen in medical offices and clinics
as well as in the emergency department setting, and it has been frequently
misdiagnosed. When dealing with a psychiatric emergency, the nurse must
be knowledgeable and skillful in identification and evaluation of this
group. Virtually any trauma to the head can potentially result in a traumatic
brain injury and affect the function of the brain.
How
many times have you taken care of patients who come to an emergency room
after having been in an auto accident? The patient is examined and there
is no visible sign or symptom of trauma. Although the patient may complain
of pain, dizziness or confusion, everything appears normal on physical
examination and the patient is sent home. Cognitive or behavioral changes,
especially if mild, are commonly attributed to the psychological effects
of the accident, and the staff, family and friends may even suspect that
the patient is faking it to get attention or for law suit purposes.
Days
or even weeks later the patient has experienced disturbed sleep patterns
and starts to develop behaviors that could be considered disturbed: confusion,
irritability, and poor impulse control. He may even be hostile and aggressive,
posing a danger to self and to others. The initial injury may not be recalled
or reported, especially if it was dismissed as inconsequential by medical
personnel at the time. Is this a bipolar disorder? Is the patient experiencing
a schizophrenic episode? What does the psychiatrist say? What does the
neurologist say? All too often the patient is diagnosed with a psychiatric
illness, and inappropriate treatments, if any, are offered.
Traumatic
brain injury and related syndromes are complicated conditions that often
are considered a gray area of psychiatry, medicine, neurology, nursing
and law practice. It is the unfortunate patient who is incorrectly diagnosed.
A vicious cycle develops. If the patient does not respond to the psychiatric
medications, the physician or psychiatrist may increase the dosages. As
the need for increased medication continues, the patient is looked upon
as severely psychiatrically disabled; when, in fact, the true etiology
is neurological trauma and requires an entirely different approach to
patient care. Just imagine the increasing frustration of the patient.
All of a sudden, he has become a mentally disabled individual.
In
many cases of head trauma, there are no concrete lab and/or x-ray findings.
Even structural and space occupying lesions such as subdural or epidural
hematomas and brain contusions may not show up immediately after the injury,
but develop relatively slowly over time. The more common injuries, especially
those resulting from motor vehicle accidents, involve damage to the axons
of individual nerve cells as the brain twists and turns on its axis and
bounces against the surface of the skull from the forces of the impact.
These may be accompanied by tiny punctate hemorrhages of the surrounding
capillaries which are similarly stretched and torn, but otherwise remain
invisible to neuroimaging techniques. Swelling may also add to the problem.
Recovery of cognitive functions may take months to years, and is based
on healing of injured brain tissue as well as compensation through use
of alternative neural pathways.
Appropriate
rehabilitation and consultation can be of significant benefit to the patient
throughout this recovery process. Misdiagnosis may deprive the patient
of needed treatment, while prescription of unneeded psychotropic medications
may complicate the underlying neurological problem. Head trauma patients
who present a psychiatric emergency need to be treated for the immediate
behaviors they exhibit. After the psychiatric emergency is dealt with,
an in-depth and on-going evaluation must take place. The nurse can help
to discover the etiology of the present problem by making an accurate
and comprehensive on-going nursing assessment, with careful evaluation
of the effectiveness of the interventions made.
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