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Pain Management

Online Course #3004 or #2004 - 5 Contact Hours

Author: Kim Marie Falk, RN, MSN.
©2008 National Center of Continuing Education, Inc.

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Purpose and Goals

SpacerWe, as healthcare professionals, must do our part to provide patients with adequate pain management. One way is through education. This course presents material to educate the healthcare practitioner about pain: its pathophysiology, influencing factors, assessment techniques, and interventions. It also addresses common misconceptions about pain and pain management.


Instructional Objectives

SpacerAfter completing this course the motivated learner should be able to:

  1. Define pain.
  2. Name the three nociceptors involved in pain sensation.
  3. Define pain threshold and pain tolerance.
  4. List five factors that influence pain perception.
  5. List four misconceptions that are barriers to pain management.
  6. Name the parts of the assessment mnemonic PQRST.
  7. List several physical and behavioral signs and symptoms of pain.
  8. List the non-opioids, opioids, and adjuvant medications used to treat pain.
  9. List six non-pharmacologic options for pain management.
  10. Name three principles of pain treatment.
  11. Outline current nursing standards for pain management.

Introduction

SpacerThe topic of pain is an important one for every healthcare practitioner. Pain is one of the most common reasons people enter the healthcare system; yet it is also one of the most widely under-treated health problems. Untreated and inadequately treated pain causes suffering and financial burden to both patients and society. "We don't have a lot of statistics about pain, but the ones we do have are frightening," notes Dr. Fred Goodwin, former Director of the National Institute of Mental Health. "In a study of 1,500 people in Michigan last year, one out of five reported that they experience chronic, ongoing pain; of those people, two out of five say that pain affects their relationships and their work." Almost half had experienced pain-related depression, and one in ten had thoughts of suicide. Over 26 million people suffer with chronic back pain, and one in six of us have pain from arthritis; but medical treatment of the pain has proven ineffective for 40% of these patients. Moreover, studies have shown that three of every four surgical patients and more than two of every three cancer patients report inadequate pain relief.
SpacerRecognizing the importance of adequate pain management, the Joint Commission on Accreditation of Healthcare Organizations (JCAHO) has recently approved new standards for pain management. It is hoped that the implementation of these standards will result in an improvement in pain management within our healthcare system.


Pathophysiology of Pain

SpacerPain is a term every healthcare practitioner is familiar with, from the professional standpoint as well as through personal experience. However, beyond knowing what pain personally feels like, healthcare practitioners need to know what causes pain and the best ways to manage it in order to give patients excellent care. Though the experience may seem simple - you stub your toe, then you feel pain - pain has been defined in numerous ways.
SpacerAs a basic scientific definition, pain is a sensation caused by some type of noxious stimulus. From the behavioral aspect, pain is a pattern of responses that function to protect an individual from harm. The International Association for the Study of Pain (IASP) defines pain as "an unpleasant, subjective sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage." Within nursing, one of the most popular definitions has been the one coined by Margo McCaffery: "Pain is whatever the experiencing person says it is, existing whenever he says it does."
SpacerCertainly all these definitions describe pain; it is a multi-factorial phenomenon. For the sake of clarity, pain can be divided into two basic components, physical and emotional. From the physical standpoint, almost every tissue found in the human body contains pain receptors, called nociceptors. It has been estimated that the skin may contain as many as 1,300 nociceptors in one square inch. These nociceptors respond to thermal, chemical, and mechanical stimuli through a-delta, C, and a-beta fibers. The a-delta receptors contain small, myelinated fibers that rapidly transmit acute, sharp pain signals from the peripheral nerves to the spinal cord. C receptors have larger, unmyelinated fibers that transmit pain at a slower rate and are commonly associated with long lasting, burning pain sensation. The a-beta receptors respond to non-painful touch, such as a gentle rub or pressure.
SpacerPhysiologically, both the peripheral and central nervous systems are involved with pain perception. The peripheral nerve fibers first convey the painful stimuli to the spinal cord. Numerous ascending pathways transmit the stimuli through the dorsal root of a spinal nerve, ending in the dorsal horn of the spinal gray matter. In the substantia gelatinosa, located in the dorsal horn, the stimuli are directed to various parts of the spinal cord. Long nerve fibers, termed spinothalamic axons and spinoreticular axons, cross over to the opposite side of the spinal cord and ascend to the brain in the anterolateral column of the spinal white matter. The interactions between these pathways are complex, involving multiple influences, chemicals, and neurological processes. However, it is this intricate system of neurological processes that enables humans to determine the presence, location, nature, and intensity of pain. Pain perception also involves descending pathways, which have been theorized to be principally involved with pain modulation.

Spacer In response to the tissue damage from the noxious stimulus, pain-producing substances are released into the extracellular fluid surrounding the pain fibers. These substances include bradykinin, cholecystokinin, serotonin, histamine, potassium ions, norepinephrine, prostaglandins, leukotrienes, and substance P. The first six chemicals stimulate, whereas the latter three chemicals sensitize the a-delta and C fibers. But the brain and spinal cord also produce pain relieving substances, endorphins and enkephalins. These chemicals attach to endogenous receptors in the brain, spinal cord, and peripheral tissues, activating the descending inhibitory system. The descending opioid-related pain inhibitory system was proposed by Fields and Basbaum and describes several centers in the brain that produce analgesia. The release of endorphins can be triggered by many situations, particularly those entailing stress, fear, or excitement. Aerobic activity can also stimulate endorphins.
SpacerFrom the emotional standpoint, the interconnectedness of thoughts, feelings and beliefs plays a part in pain perception. Research has shown that people experience more pain when they focus on it, are told to expect one thing but experience something different, expect a high level of pain, and are tense and under stress. It has been theorized that structures in the brain are closely involved with the emotional aspects of pain perception. It is believed that stimuli are filtered through the limbic-hypothalamic system and that the frontal cortex influences rational interpretation and response to pain.
SpacerThough physical pain reception is a universal human phenomenon, people experience different pain thresholds and tolerances. Pain threshold is the earliest point at which a person perceives stimuli as painful. Most researchers conclude that there is little variation in pain threshold, from person to person and from situation to situation. However, it has been noted that repeated exposure to noxious stimuli can lower a person's threshold, even if only minimally. This may be due to increased nociceptor sensitivity; when nociceptors are already stimulated less stimulus is needed to produce pain. Pain tolerance refers to the lowest level of stimulation at which a person will stop or seek to stop the stimulus. It is very individualized, different from person to person and from situation to situation.
SpacerOne theory that attempts to explain both the psychologic and physiologic aspects of pain is the Gate Control Theory. (See Figure 1.)


Gate Control Theory of Wall and Melzack

Gate Control Theory Diagram
  1. The projection neuron (P) carries both nociceptive stimulation from small fibers (S) and non-nociceptive simulation from large fibers (L) on the way to the brain.
  2. With no stimulation, the inhibitory neuron (I) keeps the gate "closed," and there is no painful sensation.
  3. With painful stimulation, the small fiber (S) blocks the inhibitory neuron (I), "opening" the gate for the projection neuron (P) to send on the painful stimulus.
  4. With the addition of non-painful stimulation, the large fiber (L) activates the inhibitory neuron (I), partially or completely closing the gate depending on the strength of the stimulation, and competes with the painful stimulation for access to the projection neuron (P).
Figure 1

SpacerFirst proposed by Melzack and Wall in 1965, it has undergone numerous modifications, and is still being used today to explain pain. The theory proposes that the transmission of noxious stimuli is modulated by a gating mechanism in the dorsal horn. These theoretical gates can be opened or closed to either allow for or prevent pain transmission. The stimulation of smaller fibers opens the gate; the wider it is opened, the more pain occurs. However, stimulation of large fibers closes the gate, inhibiting pain transmission. It is these large fibers that are thought to selectively activate cognitive processes. The gate can also be closed by messages from higher brain centers; therefore, both ascending and descending systems are involved to control pain impulses and reduce pain intensity.
SpacerPain can be categorized either by its origination or duration. Categories of origin include cutaneous, somatic, visceral, neuropathic, and referred. Cutaneous pain is a direct, acute, and localized sensation activated within the epidermis, dermis, or subcutaneous tissues. A pinprick or paper cut is an example of cutaneous pain. Somatic pain originates from the musculoskeletal system, from structures such as the tendons, ligaments, muscles, joints, bones, blood vessels, and nerves. It is felt as a scattered or diffuse sensation such as the pain experienced by a sprain. Visceral pain is a diffuse, poorly localized feeling emanating from body organs with hollow cavities, such as the cranium, thorax, and abdomen. Appendicitis often causes visceral pain. Neuropathic pain results from damage to either the peripheral or central nervous system. Typically, neuropathic pain is caused by non-noxious stimuli and has a delayed onset. Many people describe neuropathic pain as a burning with periodic stabbing sensations. When pain is felt in a part of the body away from the site of injury it is known as referred pain. Pain can also be categorized in other ways, many of which involve specific sites such as headache and phantom limb.
SpacerPain that is of short duration (less than six months) is called acute; whereas prolonged pain (six months or greater) is termed chronic. However, chronic pain is not necessarily acute pain that has persisted. Most often, the cause of acute pain is known and the course of healing follows a predictable pattern. With chronic pain, treatment does not eradicate the pain, the cause of which may or may not be known. Of importance is that a person experiencing acute pain usually manifests signs and symptoms caused by stimulation of the sympathetic nervous system such as an increase in heart rate, respiratory rate, and blood pressure. However, many people suffering from chronic pain do not demonstrate these objective physical signs but rather experience sleep disturbances, irritability, lack of energy, depression, and even lifestyle or personality changes. Chronic pain can have an insidious onset with characteristics that change over time.


Influencing Factors

SpacerCertainly people of all ages are capable of feeling pain. Two particular age groups with special needs include children and older adults. Nonverbal children will not be able to articulate the presence of pain, nor describe its characteristics. The practitioner must be alert to nonverbal cues such as excessive crying, grimacing, and restlessness. Even those children that can speak may have difficulty expressing their feelings. Therefore, the practitioner needs to be very astute when assessing children for the presence of pain.
SpacerThe other age group with special needs includes the older adult. Many older adults assume that pain is a natural part of aging; this is untrue. What is true is that the incidence of disease and illness increases as we age and pain is a common accompanying symptom. Practitioners need to inquire about and then explore older adults' areas of pain. Treatment of the diseases and illnesses present is of utmost importance in achieving pain relief.
SpacerWhile studies have been conducted on pain threshold and pain tolerance in relationship to age, many conflicting results have been documented. Considering the elderly, two researchers concluded that pain threshold increases but pain tolerance decreases with age. However, numerous other researchers have criticized studies conducted on older adults' pain thresholds and tolerances, citing attitudinal bias, delayed reaction times, physical impairments, and cognitive deficits as variables not taken into account. One would suspect that the changes that often accompany aging do affect the pain experience.
SpacerIn respect to gender, in the American culture men have typically been socialized to deny or conceal their pain, while women are often encouraged to be demonstrative with their reaction to pain. Phrases such as, "Be a big boy and don't cry" and "You just let it all out now, girl" are part of the American culture. Some researchers have theorized that estrogen is instrumental in regards to modulation of pain sensitivity. Others have demonstrated that the physical and emotional experiences of pain are similar for both genders, while it is the expression that often differs. Nonetheless, very few studies support gender differences in pain threshold. Most scientists believe that social influences, not physical differences, contribute to variations in the pain experience.
SpacerAnother aspect of culture is the patient's environment: how he was raised and where he is currently situated. Many nurses are familiar with patients who are more expressive of their pain when family are present and those that remain stoic even in obviously painful situations. When assessing for pain consider factors such as: is the patient generally vocal or quiet and does he seek and trust the healthcare environment? For the patient who is quiet or distrustful of health care, you may need to actively elicit more information and work to establish trust before you can get an accurate pain assessment.
SpacerAs mentioned earlier, emotional state affects pain. Any additional stressors can aggravate the pain experience. Many times anxiety is also present with pain, causing an increased perception of pain intensity. Other psychological factors affecting pain include fatigue and depression.
SpacerFamily and social support are usually helpful to patients when dealing with pain. Often patients have their own strong support systems already established and find this helps them to manage the emotional aspect of pain. Sometimes the practitioner needs to assist patients to utilize or even establish support systems. For example, if the patient is agreeable, facilitating visits from family and friends may be necessary. Many people assume that those who experience pain like to be alone but this is not always true, particularly for those that experience chronic or episodic, recurring pain. Studies have shown that when people do not have adequate social support, or perceive insufficient support, they have more complaints of pain and reduced psychological well being. Formal support groups have been established for many circumstances and nurses can be instrumental in connecting patients to these resources.


Misconceptions

SpacerThere are many misconceptions among healthcare workers that are barriers to patients receiving adequate pain management. One of the most common and persistent myths is that drug abusers overreact to pain. Many times healthcare workers assume that drug abusers are always seeking to satisfy their addiction and not eliminate actual physical pain. While it is true that part of the drug-abusing syndrome involves drug-seeking behavior, it is also true that people who abuse drugs can experience pain. In fact, changes in the central nervous system related to drug abuse may result in an exaggerated physiologic response to pain stimuli; thus your drug abusing patient may be less tolerant of pain than someone who doesn't use drugs, and he may be suffering more intensely than the patient in the next bed. As with all people, this pain deserves to be treated effectively. Even though studies have shown that drug abusers tend to need higher doses of pain medicine than the general population due to this tolerance, doctors often prescribe lower doses of narcotics or substitute nonnarcotics.
SpacerAnother misconception lies in the belief that minor illnesses and injuries are less painful than severe ones. However, the amount of tissue damage is not a predictable factor for pain intensity. In fact, when pain receptors are destroyed in a severe injury the patient can experience little or no pain. Additionally, many disorders manifest themselves differently among patients; and each patient can encounter great fluctuations, predictable or unpredictable, in their pain.
SpacerOne of the most widespread myths among healthcare workers and the general population is that the regular use of analgesics, particularly narcotics, leads to addiction. This misbelief is rooted in a misunderstanding of the terms tolerance, physical dependence, and addiction. Tolerance is a physical occurrence that will result after repeated administration of a narcotic. A person will need a larger dose of narcotic to gain the same level of pain relief. This is an expected side effect when narcotics are administered over a period of time. Physical dependence is also a physiologic phenomenon that occurs when narcotics are abruptly stopped and the person undergoes a withdrawal syndrome. However, addiction is when a patient's psychological need for a drug exceeds his physical need. An addicted patient becomes overwhelmingly involved with obtaining and using a drug for its psychic effects. Only a very small minority of patients, less than 1%, actually develops addiction when they are prescribed narcotics for pain. Most often, narcotics are prescribed on a short term basis for severe pain, but their use as appropriate for long term pain, such as in terminal cancer, has been well supported.
SpacerLastly, because pain is subjective, the best authority on the patient's pain is the patient himself. However, many healthcare workers consider themselves the expert on the patient's pain. While it is true that healthcare workers often have more knowledge about pain in general, this does not negate the fact that the patient is the only one experiencing the particular pain being treated. This is a very important point to remember when assessing and treating pain. One study of elderly patients' and nurses' pain ratings found a significant difference between when nurses and patients thought pain should be treated. Additionally, the nurses tended to underestimate severe pain and overestimate mild pain. This emphasizes the need to continually involve the patient in the treatment process. The most effective treatment occurs when healthcare workers and patients work together to relieve pain.


Assessment

SpacerThe American Pain Society stresses that clinicians should consider pain the fifth vital sign, thus elevating it to an importance given to the measurements of temperature, pulse, blood pressure, and respirations during patient assessments. Unfortunately, inconsistent and incomplete assessments have been cited as major factors contributing to inadequate pain management.
SpacerOne of the most common mnemonics for remembering the steps involved in pain assessment is PQRST: Provoking factors, Quality, Region/Radiation, Severity/Symptoms, and Timing. Provoking factors include both precipitating and aggravating conditions: what brings the pain on and what makes it worse. This information may lead to the origin of the pain, if unknown, and can also be useful when teaching patients what situations to avoid or modify to help lessen or eliminate the pain. The number of provoking factors is vast and can include certain positions, movements, or activities; specific times of the day or night; and even particular emotions such as anxiety or anger.
SpacerTo ascertain the quality of the pain the nurse should ask open-ended questions, thus allowing the patient to provide his own description. If the patient is having difficulty, prompts are acceptable and should include common descriptors, for example: sharp, dull, pulling, crushing, throbbing, burning, or pricking. This information can often help determine the pain origin and can be most useful when prescribing or recommending treatment options.
SpacerThe easiest way to determine the region of pain is to ask the patient to point to or name the specific area or areas on his body. When a patient has diffuse pain, he may indicate a large area or be unable to pinpoint the exact spot. Additionally, those experiencing deep pain, such as visceral pain, may verbally describe the feeling as "deep" or "inside." Not all pain radiates; but this is a good time to ascertain if radiation is occurring and, particularly when the patient indicates a large area, to clarify if the pain is at the same intensity within the whole area. Remember, radiation is when the pain originates from the injury outward; whereas, referred pain is when the feeling occurs at a site different than the injury. Patients also can experience shifting areas of pain, where certain areas are only periodically painful.
SpacerMany tools have been developed to assist the nurse in determining the severity of pain. The use of standardized tools has several advantages. First, they are reliable and objective and thus the most accurate way to rate pain severity. Also, they take very little time and training to implement. Thirdly, the same tools can be used to assess the effectiveness of interventions. The most common tool is the visual analog scale, which features a numerical pain-rating scale. (See Figure 2.)


Figure 2
Visual Analog Scale Diagram

SpacerIt uses a 10 cm line with numbers ranging from 0 to 10. Patients point to a number that corresponds to the level of pain they are feeling. Before using the scale with a particular patient the nurse should explain the significance of the numbers: 0 represents no pain, 1-3 mild pain, 4-6 moderate pain, 7-9 severe pain, and 10 means you are experiencing the worst pain imaginable. A variation of the scale often used by health professionals is to describe verbally the 0 to 10 rating and ask the patient to state the corresponding number.
SpacerFor patients who do not have mastery of the English language or the appropriate cognitive level to use a number scale, the Wong-Baker Faces Pain-Rating Scale is an appropriate alternative. (See Figure 3.)


Wong-Baker FACES Pain Rating Scale

FACES Rating Scale

spacerExplain to the person that each face is for a person who feels happy because he has no pain (hurt) or sad because he has some or a lot of pain. Face 0 is very happy because he doesn't hurt at all. Face 1 hurts just a little bit. Face 2 hurts a little more. Face 3 hurts even more. Face 4 hurts a whole lot. Face 5 hurts as much as you can imagine, although you don't have to be crying to feel this bad. Ask the person to choose the face that best describes how he is feeling.
spacerRating scale is recommended for persons age 3 years and older.
spacerBrief word instructions: Point to each face using the words to describe the pain intensity. Ask the child to choose face that best describes own pain and record the appropriate number.

From Wong DL, Hockenberry-Eaton M, Wilson D, Winkelstein ML, Schwartz P: Wong's Essentials of Pediatric Nursing, 6/e, St. Louis, 2001, P. 1301. Copyrighted by Mosby, Inc. Reprinted by permission.

Figure 3.


SpacerThis tool depicts 6 faces ranging from a happy face to a crying grimace. The nurse reads a statement about how each face correlates to pain and then the patient points to the face that best represents how he is feeling.
SpacerBesides severity, the "S" in the pneumonic PQRST stands for symptoms. Assess the patient for other symptoms that accompany the pain. Common ones include nausea, vomiting, dizziness, and restlessness. Many times when the patient is given treatment for pain, these symptoms subside or are eradicated; but other times, adjuvant treatments are needed.
SpacerThe questions to ask in determining timing include: "How long does the pain usually last?" and "When and how does it usually lessen or stop?" The answers to these questions help the nurse to understand the precise nature of the patient's pain experience and allow the nurse to support the patient's methods of pain relief, unless they are harmful.
SpacerBesides using the PQRST mnemonic, the nurse must be alert for various physical and behavioral signs and symptoms associated with pain or those that may accompany pain. The nurse may observe some of these behavioral indicators, such as restlessness, moaning, crying, clenched teeth, or protecting /guarding body parts. Or the patient may need to state their presence, such as when he is feeling anxious or nauseous. Vital sign changes can also indicate pain, such as an elevation in pulse rate, blood pressure, and respirations. However, this is more accurate for the presence of acute, not chronic, pain. Also, elevated vital signs are not always seen in every acute pain situation, nor are they a reliable indicator of pain intensity. Therefore, the absence of behavioral indicators or vital sign elevations does not mean the patient is not experiencing pain. For example, it is unclear whether a comatose person experiences pain; just because a person cannot respond to a noxious stimulus may not mean that he cannot feel it. Conversely, these other signs and symptoms may be the only clue the nurse has that the patient is in pain. This is particularly significant when the patient has difficulty expressing pain due to factors such as socioculturally learned behaviors, immaturity, neurologic damage, or mental or physical handicap.
SpacerAnother area for the nurse to observe is how the patient's pain is affecting activities of daily living (ADLs). When a patient is in pain, ADLs are often either neglected or altered. Sleep can become erratic, sexual activity may decline, exercise programs can cease, playtime or hobbies are neglected and the patient may miss more hours at work. Simply asking patients, "How does pain limit your daily activities?" or "What can you no longer do because of your pain?" may elicit useful information.
SpacerAnother important area for the nurse to consider when assessing the patient's pain is neurological status. When deficits are present in the central nervous system, such as dementia, mental handicap, or even immaturity, the nonverbal cues of pain become most important. Though it is more difficult to assess a patient with cognitive impairment, it is not impossible; every person deserves a thorough pain assessment. Behaviors that can indicate pain include flinching, guarding, grimacing, whimpering, and restlessness. Additionally, further investigation is warranted when a patient refuses to move or eat, pulls at equipment such as tubing, or has a change in continence. When the patient has a peripheral nervous system deficit, such as the diabetic with peripheral neuropathy, the sensation of pain in certain parts of the body is altered. Teaching the patient with peripheral nervous system deficits to visually inspect his body on a daily basis is important; injuries can occur without the sensation of pain as a warning. Also, careful application of certain treatments, for example hot or cold packs, is essential.


Pharmacologic Interventions

SpacerOnce a complete assessment has been done, the patient needs to receive treatment in a timely manner. The key to any treatment plan is individualization, for each patient and sometimes each pain episode. Often a variety of resources are needed for pain control. Certainly the goal is pain eradication, but sometimes bringing pain to an acceptable level of tolerance is more realistic. Pharmacological intervention is usually a good place to start. The three main categories of pharmacologic pain relief medications are non-opioids, opioids, and adjuvants.
SpacerSpecific examples of commonly used non-opioid pain medications, often called non-narcotics, include acetaminophen, aspirin, nonsteroidal anti-inflammatories (NSAIDs), choline magnesium trisalicylate (Trilisate), and diflunisal (Dolobid). Acetaminophen's analgesic properties appear to involve central mechanisms associated with nitric oxide and N-methyl-D-aspartate receptors. Aspirin, other salicylates, and NSAIDs inhibit prostaglandin synthesis to produce analgesia.
SpacerCommon opioid medications, sometimes referred to as narcotics, are typically characterized as either weak or strong. Weak opioids include codeine, oxycodone, Vicodin, and oxycodone combined with either acetaminophen or aspirin. Morphine, hydromorphone, fentanyl, and meperidine are examples of strong narcotic medications. The opioids can also be classified by two subtypes: agonists and agonist-antagonists. Both types of opioids provide analgesia through mu, delta, and kappa receptors found in the central and peripheral nervous systems. The agonists attach to mu, delta, and kappa sites; however, the agonist-antagonists bind to the mu and kappa receptors, producing effects at the kappa sites but blocking effects at the mu sites.
SpacerAdjuvant medications can also be used to supplement non-opioid and opioid medications. Adjuvant analgesics are medications whose primary indication is not for pain management but which have demonstrated analgesic effects. Examples of adjuvant medications used to treat pain include tricyclic antidepressants and anticonvulsants. Tricyclic antidepressants help to improve mood and increase pain threshold. The analgesic action of tricyclic antidepressants is not certain; however, it has been theorized that they enhance the descending pain inhibitory system through prevention of serotonin and norepinephrine re-uptake. They have been found to be particularly useful for treating some types of migraines and burning types of pain. Examples of tricyclic antidepressants include amitriptyline and nortriptyline. The anticonvulsants' mechanism for pain control is also uncertain; however, they have been found to be particularly useful in treating lancinating and neuropathic pain. Carbamazepine, valproate, and gabapentin are three examples of anticonvulsants used to treat pain.
SpacerThe medication chosen to treat pain is often based on practitioner's preference; however, certain restrictions apply. Generally, a patient should not be taking two analgesics from the same class at the same time, unless one is sustained release used on a round-the-clock basis and the other is instant release for breakthrough pain. When a patient needs to switch from one narcotic to another, due to ineffectiveness or intolerable side effects, health practitioners should consult an equianalgesic guide. An equianalgesic chart shows practitioners the equivalent potency regarding dosage and route between narcotics, helping to eliminate the possibility of under or overdosing. Educate patients to ask for pain medication when the pain begins, not when it becomes unbearable. Pain control methods work best when they are administered at the onset of pain. Also remember to check patients' allergies before administering any medication.
SpacerIn addition to administering medications, nurses are also responsible to know the potential side effects of each medication. Every medication has the potential for side effects, even if the patient has had the medicine before and not experienced a particular side effect. Also, be aware that side effects may occur at lower doses among the older adult population. With the exception of acetaminophen and Trilisate, the non-opioids have antiplatelet effects that can lead to bleeding, particularly in the gastrointestinal tract. Nausea and vomiting have also been associated with the non-opioids. Acetaminophen may cause hepatotoxicity, but this is rarely seen except for overdose or when used with people who have a compromised liver. Be aware that for each non-opioid there is a ceiling dose. The ceiling dose is the highest level of analgesia that can be achieved without significant side effects or toxicity.
SpacerThe most troublesome side effect of the opioids is constipation. Fortunately, concurrently instituting a bowel regimen usually helps to eliminate this side effect. A good bowel regimen includes the daily use of a stool softener plus a laxative, increasing fiber and fluid intake, and instituting routine aerobic exercises. Opioids can also cause sedation, nausea, and vomiting. As with any sedating medication, caution must be instituted when performing physical activities. An antiemetic can be prescribed for relief of nausea and vomiting. Fortunately, tolerance generally develops to sedation, nausea, and vomiting. Respiratory depression is a potentially serious side effect of opioids but fortunately not a very common one. If respiratory depression does occur, it tends to be a short-lived phenomenon. Additionally, using the antagonist medication naloxone can reverse respiratory depression. However, because the half-life of naloxone is shorter than most opioids, the patient must be monitored closely for recurrence of respiratory depression. Also, using naloxone can reverse the analgesic effects of the opioid; therefore, the patient may need further treatment to control his pain.
SpacerBesides the choice of medication, the way a medication is administered is also important. Options include enteral and parenteral medications. Enteral medications are those that use the gastrointestinal (GI) tract, while parenteral medications bypass the GI system. If the GI system is intact, this is usually the best choice. When parenteral medication is preferred there are several notable options: local pain relief, epidurals, rectal administration, and patient controlled anesthesia.
SpacerLocal pain relief can involve a topical application to the skin or mucous membranes. One popular use of topical pain relief, particularly among the pediatric population, has been the use of a cream mixture of prilocaine and lidocaine applied to the skin before an intravenous insertion is performed.
SpacerAnother way to administer parenteral medication is through an epidural. An anesthesiologist or anesthetist places a catheter into the epidural space in the spine, securing it with a sterile dressing and tape. Medication is either administered continuously through a pump or intermittently by the anesthesiologist or anesthetist. Usually the catheter placement is temporary and exits out the back; however, long-term epidurals can be performed and they often exit through the abdomen. The nurse's responsibility to a patient who has an epidural includes making sure the catheter is securely in place, usually taped to the skin, and informing the anesthesiologist or anesthetist when the patient on intermittent dosing needs more medication to be injected into the catheter. Advantages of the epidural route include site-specific, rapid and prolonged pain relief with less severe systemic adverse side effects.
SpacerAn often-neglected route is rectal administration. Advantages of the rectal route include simplicity of administration and lower cost than most other parenteral methods. To administer, position the patient on his left side with top leg flexed, while aiming toward the patient's umbilicus insert a moistened suppository against the rectal wall approximately a finger's length into the rectum, and after withdrawing your finger ask the patient to relax and not bear down. Briefly holding the patient's buttocks together may aid in eliminating expulsion. While suppositories are most often the products given rectally, solutions, injectable medications, and even tablets have been used with little or no alteration. Contraindications of the rectal route include neutropenia (low white blood cell count), thrombocytopenia (low platelets), and rectal bleeding.
SpacerAnother very effective method of parenteral pain medication administration entails the use of patient controlled anesthesia (PCA). The effectiveness of PCA is based on its individualization, a primary component of pain management. With PCA the patient receives either intravenous or subcutaneous medication when he presses a button on the PCA machine to which he is attached. The nurse, following prescriptive order, presets the medication, dosage, and timing before the patient is attached to the machine. The machine can be set to include a lockout time. This is when the patient can push the button to deliver medication but no medicine is released until a certain time elapses, thus preventing overdose. However, it is very important to monitor patients who are on PCAs, particularly in the initial stage of operation. Areas for potential problems include machinery malfunction, a too strong prescribed dosage, or a too short or too long lockout time. Additionally, patients must be educated on how to use a PCA machine. When a patient is on PCA a nurse should include, as part of the pain assessment, whether the patient understands how PCA works and how to use it to obtain medication. Luckily, PCA machines are easy to use and have the advantage of giving the patient control of his own pain relief. An additional advantage is that patient's serum drug levels can remain constant since the moment he feels pain, he can push a button to receive medication. When patients rely on nurses for pain medication, relief takes longer since the patient must notify the nurse he is feeling pain, the nurse must check the medication order, then pour the medication, before she can finally give it. An exciting new development is the use of PCA for treating pain in children and adolescents.
SpacerA simple, widely used, and effective approach to pharmacotherapy for cancer and other pain has been devised by the World Health Organization (WHO). The five essential concepts in the WHO approach to drug therapy of pain are:

  • By the mouth.
  • By the clock.
  • By the ladder.
  • For the individual.
  • With attention to detail.

SpacerIt has been shown to be effective in relieving pain for approximately 90 percent of patients with cancer and over 75 percent of cancer patients who are terminally ill. Called the WHO Pain Ladder, this approach incorporates the concept of an analgesic ladder, a rational, stepwise approach to pain management.
SpacerThe first step in the ladder is the use of acetaminophen, aspirin, or another NSAID for mild to moderate pain. Adjuvant drugs to enhance analgesic efficacy, treat concurrent symptoms that exacerbate pain, and provide independent analgesic activity for specific types of pain may be used at any step.
SpacerWhen pain persists or increases, an opioid such as codeine or hydrocodone should be added (not substituted) to the NSAID. Opioids at this step are often administered in fixed dose combinations with acetaminophen or aspirin, because this combination provides additive analgesia. Fixed-combination products may be limited by the content of acetaminophen or NSAID, which may produce dose-related toxicity. When higher doses of opioid are necessary, the third step is used. At this step separate dosage forms of the opioid and nonopioid analgesic should be used to avoid exceeding maximally recommended doses of acetaminophen or NSAID.
SpacerPain that is persistent, or moderate to severe at the outset, should be treated by increasing opioid potency or using higher dosages. Drugs such as codeine or hydrocodone are replaced with the more potent opioids (usually morphine, hydromorphone, methadone, fentanyl, or levorphanol), as described above. Medications for persistent cancer-related pain should be administered on an around-the-clock basis, with additional "as-needed" doses, because regularly scheduled dosing maintains a constant level of drug in the body and helps to prevent a recurrence of pain. Patients who have moderate to severe pain when first seen by the clinician should be started at the second or third step of the ladder.
SpacerThe topic of placebos is controversial. A placebo is any inactive substance given to satisfy a demand for medication. Studies have been done to demonstrate the effectiveness of placebos; however, many healthcare practitioners deem the use of placebos as unethical. Some studies have demonstrated that the effectiveness of placebos may be due to the body's release of endorphins or even the presence of the healthcare worker. Essentially, when a practitioner prescribes placebos he negates the subjectivity of pain because he has labeled the patient's pain as not real and therefore, not needing an active treatment. Those patients who are prescribed placebos are often seen as liars, drug seekers, or mentally ill. Certainly, when one prescribes or gives a placebo, there is the potential that the trust relationship, so important within the healthcare arena, could be destroyed.


Non-Pharmacologic Interventions

SpacerBesides medications there are also non-pharmacologic options to control pain. Most often they are used to complement pharmacologic options. The advantages of using non-pharmacologic methods include the fact that many of them do not require a prescription or any special equipment. However, always make sure an intervention is appropriate and safe for each patient situation before implementation.
SpacerThe simplest way to eliminate or reduce pain can involve altering the environment. Many variables within the patient's setting can cause or worsen pain such as temperature, bedding, body alignment, equipment, and clothing. Adjusting the air-conditioning, adding a fan, or removing or supplying a blanket can help the patient who is uncomfortable due to temperature. Wrinkles in sheets can cause extra friction and pressure, which can be relieved by tightening and smoothing linens. Adding an eggcrate mattress can improve old or unsupportive mattresses. Positioning in anatomical alignment, providing support for limbs, and eliminating pressure points are important ways to prevent pain from occurring in the immobilized patient. Therapeutic beds can also relieve pressure. Encouraging active range-of-motion exercises or providing passive range-of-motion can alleviate pain caused from stiffness and prevent painful muscle contractures. Equipment can cause pressure points and friction areas and therefore must be routinely checked for proper placement, with frequent skin assessments. For example, a nasal cannula can cause erosion of nares or ear tissue, or tubing can become lodged underneath the patient. Also, patient clothing, whether a gown or street clothes, can become tangled or caught on equipment, causing constriction and pain. Wet clothing can also become an irritant.
SpacerOther non-pharmacologic interventions are relaxation and guided imagery, often used together. Relaxation can be as simple as focusing on one's breathing to control tachypnea or mentally concentrating on a pleasant thought or scene. Patients can also be taught to progressively contract and then relax various muscle groups, usually in a sequential pattern, such as from neck to toes. Meditation is a form of relaxation. Guided imagery generally implies that a trained practitioner reads or speaks in soothing tones while the patient focuses on a positive image, such as a beach scene or a walk in the park. The key points of guided imagery involve focusing on a repetitive thought, word, phrase, or activity and taking a positive attitude toward intruding thoughts, eliminating them as distractions. Relaxation and guided imagery are thought to counterbalance the "fight or flight" response the body often activates in response to pain. As a result of using these techniques the body often experiences a reduction in skeletal muscle tension, a decrease in vital signs, lowered metabolic rate, and less oxygen consumption.
SpacerCutaneous stimulation can be used to eliminate pain as well. The therapeutic effects of cutaneous stimulation are based on the Gate Control Theory of pain discussed earlier. Cutaneous stimulation focuses on non-painful peripheral skin surfaces, thereby blocking the painful stimulation, causing a decrease in pain. Techniques that use cutaneous stimulation are massage, acupressure, acupuncture, hot and cold applications, and transcutaneous electrical nerve stimulation (TENS).
SpacerMassage involves using either the hands or a smooth hard object, such as a sandbag, to hold, clutch, knead and rub the skin and superficial muscle layer. Particular attention is given to areas of pain. In its simplest form, a person may automatically massage a painful area; however, the use of professional massage therapists is growing in popularity.
SpacerBoth acupressure and acupuncture originated in China. Acupressure entails massaging and/or applying pressure to trigger points. Trigger points are hypersensitive areas in connective or muscle tissue. Acupuncture also uses trigger points but instead of massage, fine sterilized flexible needles are placed at these sites. After the needles are inserted under the skin, the practitioner agitates the needles in order to produce pain relief. Pain relief is based on the belief that health is a state of constantly changing flow of energy which, when unbalanced, causes disease and pain. Acupuncture is thought to help regulate the body's energy flow back to a state of balance. Though the energy flow theory has not been proven, it has been demonstrated that acupuncture stimulates the body's endorphins and monoamines.
SpacerHeat has been found effective in soothing inflamed muscles and helping to reduce inflammation, particularly for post-traumatic pain, rheumatic aches, and neck and back pain. It is best used after initial inflammation has resolved, usually twenty-four hours after injury occurs. Also, heat can be applied before mobilization is attempted, allowing for a greater degree of movement as well as increased comfort. When heat is applied there is increased blood flow, decreased vasomotor tone, and increased tissue metabolism providing overall effects of analgesia, reduced muscle spasticity, sedation, and elevation of the pain threshold. Heat should not be used, however, at the site of neoplasms, skin desensitization, vascular insufficiency, active infection, or bleeding.
SpacerCold application can be as effective as heat and is usually the first application in an initial acute injury. Cold reduces inflammation and swelling through decreasing vascular flow. It is useful to lessen muscle spasticity and may elevate pain threshold by reducing nerve conduction velocity. Contraindications for cold therapy include vascular insufficiency and conditions directly aggravated by cold, such as Raynaud's syndrome. Both hot and cold are useful for analgesia, and the choice may be simply a matter of patient preference.
SpacerA TENS unit is a portable machine attached to the patient's skin at specific trigger points or peripheral nerves near the site of pain. The practitioner applies the unit and then, with patient input, adjusts the placement, frequency, and voltage. A TENS unit can either be set for continual or periodically delivered electrical stimulation in order to provide for optimal pain relief. The electrical current stimulates sensory cutaneous nerve endings that are thought to block deeper, more painful sensations. Additionally, TENS may stimulate the release of endorphins. Patients report that the stimulus feels like a pricking or buzzing sensation. TENS has been found to be very effective for certain types of pain such as rheumatic aches, back and neck pain, stump pain, postoperative pain, and neuralgia. People with cardiac arrhythmias or pacemakers should not use a TENS unit. Also, TENS should not be placed over an open wound nor on areas of desensitivity.
Spacer Another non-pharmacologic treatment option is biofeedback. Biofeedback requires the use of special equipment and trained practitioners, which can be a costly endeavor. The patient is taught, through systematic trial and error, to condition brain wave activity. The patient is attached to a machine that relays information to him about body changes occurring and thus, he learns to control or replace those associated with pain with a more pleasant experience. Biofeedback has been found to be effective for a variety of painful conditions including headaches and osteoarthritis.
SpacerTherapeutic touch is based on an eastern philosophy of energy manipulation. A trained practitioner does not actually touch the patient but rather directs the patient's energy by moving her hands above the body part experiencing pain. The practitioner must center herself, make an assessment of the patient, unruffle the field, direct and modulate the energy, and also recognize when to stop. Proponents of therapeutic touch believe it to be a healing therapy that can also decrease pain. However, due to spiritual conflicts, some healthcare workers and patients have declined to participate in therapeutic touch.
SpacerLastly, never underestimate the value of education. A well-informed patient is usually best able to cope with his pain. The nurse should not be the only person in the nurse-patient relationship with the proper information on pain and its treatment. Certainly, in today's information explosion society, patients may present with a plethora of information; however, a patient with a lot of information is not synonymous with an educated patient. Beyond instructing patients about pain and treatment options, nurses may need to clarify and correct misinformation.


Principles of Pain Treatment

SpacerSome principles to remember when administering pain treatments include obtaining the patient's consent before implementation, particularly for the non-pharmacologic options. Consent can be as simple as a verbal agreement to participate in the activity or the patient may need to sign an actual form. Also teach the patient to inform you of his pain before it becomes severe; pain is best treated before reaching a severe level. Likewise, assessments should occur on a routine basis so that pain does not become severe before it is treated. Be aware that people may not use the word pain but call the experience an ache or discomfort. Also, do not assume that, because the patient received adequate relief for four hours from the last medication administration, he will get the same length of relief from the same amount of medicine at the next administration. Too many variables are changing throughout the day; for instance, a painful procedure may need to be done during one time span or nighttime may occur, when endorphins are known to be lower. It is also important to consider the patient's willingness and ability to engage in treatment. The best methods will not help if the patient is unwilling or unable to utilize them.


Documentation

SpacerCertainly another integral part of pain treatment involves documentation. Things that need to be documented include the assessment findings, treatments offered and utilized, and the results of the treatments. Documentation can occur in a variety of forms, from narratives to flow charts or a combination; however, it is most important that it is done routinely in a systematic format. Documentation helps to facilitate regular reassessment and follow-up, and is essential for effective pain management. Examples of documentation forms for assessment and evaluation are included as Figures 4 and 5.


Initial Pain Assessment Tool

Date:
Patient's Name:
Age:
Room:
Diagnosis:
Physician:
Assessed by:

1. Provoking factors. What causes the pain?
2. Pain quality. (Allow patient to use own words, or use with descriptors such as sharp, dull, burning, throbbing, pricking.)
3. Location of pain. (Patient may mark directly on drawing.) Note region and radiation.

Drawing of Human Anatomy

4. Pain severity. (Scale used: ___________________)
Spacer Right now:
Spacer At its worst:
Spacer At its best:
Spacer Highest acceptable level:
Spacer Related symptoms:
5. Time Factors. Does the pain vary throughout the day? When does it start? Stop? How long does it usually last?
6. Pain related behaviors.
7. Effects on functional status and quality of life.
8. Treatment plan.

Figure 4


Pain Management Flow Chart

Patient's Name:
Date:
Physician Room:
Prescribed analgesics:

Time
Pain
Rating*
Analgesic
adm.
Other
relief
measures
R
P
BP
Level
of
arousal
Side
effects
Concerns of patient/family
Other
comments
                     
                     
                     
                     
                     
                     
*Scale used:
Figure 5

Nursing Diagnoses

SpacerTwo North American Nursing Diagnosis Association diagnoses relevant to pain are acute pain and chronic pain. (See Figure 6.)


Figure 6 - NANDA Nursing Diagnoses:

9 FEELING (1987)

Definition
SpacerA human response pattern involving the subjective awareness of information.

9.1.1 PAIN (1978, 1996)

Definition
SpacerAn unpleasant sensory and emotional experience arising from actual or potential tissue damage (International Association for the Study of Pain); sudden or slow onset of any intensity from mild to severe with an anticipated or predictable end and a duration of less than 6 months.

Defining Characteristics
SpacerVerbal or coded report; observed evidence; antalgic position; protective behavior; guarding behavior; antalgic gestures; facial mask; sleep disturbances (eyes lackluster, "hecohe look," fixed or scattered movement, grimace); self-focus; narrowed focus (altered time perception, impaired thought processes, reduced interaction with people and environment); distraction behavior (e.g., pacing, seeking out other people and/or activities, repetitive activities); autonomic responses (e.g., diaphoresis, blood pressure, respiration, pulse change, pupillary dilation); autonomic alteration in muscle tone (may span from listless to rigid); expressive behavior (e.g., restlessness, moaning, crying, vigilance, irritability, sighing); changes in appetite and eating.

Related Factors
SpacerInjury agents (biological, chemical, physical, psychological)

9.1.1.1 Chronic Pain (1986, 1996)

Definition
SpacerAn unpleasant sensory and emotional experience arising from actual or potential tissue damage or described in terms of such damage (International Association for the Study of Pain); sudden or slow onset of any intensity from mild to severe, constant or recurring without an anticipated or predictable end and a duration of greater than 6 months.

Defining Characteristics
SpacerWeight changes; verbal or coded report or observed evidence of protective behavior; verbal or coded report or observed evidence of guarding behavior; verbal or coded report or observed evidence of facial mask; verbal or coded report or observed evidence of irritability; verbal or coded report or observed evidence of self-focusing; verbal or coded report or observed evidence of restlessness; verbal or coded report or observed evidence of depression; atrophy of involved muscle group; changes in sleep pattern; fatigue; fear of reinjury; reduced interaction with people; altered ability to continue previous activities; sympathetic mediated responses (e.g., temperature, cold, changes of body position, hypersensitivity); anorexia.

Related Factors
SpacerChronic physical/psychosocial disability.


SpacerUsing the aforementioned criteria, nurses should decide which one applies to the patient's pain situation in order to be able to plan the best treatment for the patient. Additionally, when implementing procedures that may instigate pain include "Potential for Acute Pain" as a nursing diagnosis, facilitating an assessment that can either confirm or rule out its presence at the appropriate time. Depending on your institution's format, nursing diagnoses can be part of an effective documentation process.


New Standards and a New Direction

SpacerPractitioners who work with patients with cancer have long been aware of the problems caused by pain. Much of the research on pain has in fact been conducted in an effort to deal with cancer pain. Unfortunately, treatment of cancer pain is still problematic. Identified barriers include lack of knowledge and assessment skills among healthcare professionals, patient and family reluctance to report pain, fears and misconceptions concerning opioid medications, and physicians' hesitancy to prescribe adequate amounts of opioids due to fear of investigation by regulatory authorities. In order to overcome these barriers and to begin steps toward satisfactory pain management for patients with cancer, many healthcare professionals have focused on the process of institutionalizing pain management. The basic underlying principle of institutionalizing pain management is that healthcare professionals would make pain management a priority within their practice environment. The JCAHO Standards on Pain Management are in large part due to these efforts, but they affect all patients who deal with the problem of pain, not just those with cancer pain.
SpacerThe Standards outlined below were developed by the Joint Commission on Accreditation of Healthcare Organizations as guidance on pain management for healthcare organizations providing ambulatory care, behavioral health care, home care, hospice, hospital, and long term care.
SpacerThe healthcare organization addresses care at the end of life. Patients facing death need respectful, responsive care. Among the responsibilities of caregivers are managing pain aggressively and effectively, and responding to the psychological, social, emotional, spiritual, and cultural concerns of the patient and the family.
SpacerPatients have the right to appropriate assessment and management of pain. Pain management is an important part of patient care. Not only should healthcare providers be educated fully on assessment and management, but patients and their families should understand its importance and appreciate their roles in managing pain.
SpacerPain is assessed in all patients. Good patient care requires treatment of all symptoms that might be associated with a disease, condition, or treatment, including pain. The initial assessment of every patient includes pain, and appropriate treatment is provided. More comprehensive assessments may be required by the specific condition of the patient. Measures of pain intensity and quality should be used that facilitate reassessment and follow-up.
SpacerPolicies and procedures support safe medication prescription or ordering. Procedures supporting safe medication prescription or ordering address, among other issues, appropriate use of patient-controlled analgesia (PCA), spinal/epidural or intravenous administration of medications, and other pain management techniques.
SpacerThe patient is monitored during the post-procedure period. Pain intensity and quality (e.g., the character, frequency, location, and duration of pain), and responses to treatments are to be monitored continuously.
SpacerRehabilitation is designed to achieve an optimal level of functioning, self-care, self-responsibility, independence, and quality of life. Problems addressed during the rehabilitation process may include pain interfering with optimal level of function or participation in rehabilitation.
SpacerPatients are educated about pain and managing pain as part of treatment, as appropriate. Topics to be covered in patient and family education include understanding pain, the potential for pain accompanying various procedures, the importance of effective pain management, the pain assessment process, and methods for pain management.
SpacerThe discharge process provides for continuing care based upon the patient's assessed needs at the time of discharge. Pain and pain management should be addressed as part of the discharge planning process.
SpacerThe organization collects data to monitor its performance. Each healthcare organization is expected to collect and evaluate data from patients and their families regarding their perceptions of care and service. Data considered for collection include the appropriateness and effectiveness of pain management.
SpacerAdditional information on these standards may be obtained from Joint Commission on Accreditation of Healthcare Organizations, One Renaissance Boulevard, Oakbrook Terrace, IL 60181 USA Phone: 630-792-5000, or from their Web site at www.jcaho.org.
SpacerDespite the wide variety of reasons people seek healthcare, pain is one of the most common presenting symptoms found to accompany health problems. Often, pain is the main reason a person has chosen to enter the healthcare system. And though pain is a common experience, there are a wide variety of types, many influencing factors, and numerous ways to treat it. It has been noted that nurses spend more time with patients in pain than any other member of the healthcare team. Therefore, nurses have a duty to stay informed about pain so they can be competent partners with their patients towards effective pain management.


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